News and Trends-Mabnus

2024-04-29

CD71 is the iron transferrin receptor 1 (TFRC), the major cell surface iron uptake protein. Iron uptake is mediated by the internalization of the transferrin (Tf)-iron complex thro...

Structure and function of therapeutic antibodies approved by the FDA in 2023

2024-04-28

BackgroundOver the past decade, the number of new antibody-based biologics approved each year has increased significantly, with the FDA approving 100 new antibodies in the past dec...

Natural killer cells typing marker CD56

2024-04-26

CD56 is a neural cell adhesion molecule (NCAM) involved in processes such as neuronal adhesion, neurite bundling, and neurite outgrowth. CD56 is a typical phenotypic marker of natu...

Pathological study of anti-human LILRB4 antibody in a mouse model of Alzheimer's disease

2024-04-26

Background:Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly, leading to progressive cognitive impairment and ultimately death. AD pathological h...

Blood cancer therapeutic target CD45

2024-04-25

CD45 is a receptor-type tyrosine protein phosphatase C (PTPRC), also known as leukocyte common antigen (LCA). It is a type I transmembrane glycoprotein expressed on almost all hema...

The membrane attack complex inhibitor CD59

2024-04-25

CD59 is a membrane-bound protein that functions as a membrane attack complex inhibitory factor (MACIF). It acts by binding to C8 and C9 complement components of the membrane attack...

The complement inhibitor CD55

2024-04-24

Previously, we introduced the regulatory protein CD35 (CR1) in the complement system. In this issue, we will introduce another complement system regulatory protein CD55. CD55 is th...