CD74 is a cell surface receptor for the macrophage factor MIF
2024-05-15
CD74 is the MHC class II histocompatibility antigen gamma chain, also known as the HLA-DR antigen-associated invariant chain. It plays a key role in MHC class II antigen processing...
Macrophage colony stimulating factor 1 receptor CD115
2024-05-14
CD115 is a member of the macrophage colony-stimulating factor 1 receptor (CSF1R), also known as FMS kinase. It belongs to the protein tyrosine kinase family and the platelet-derive...
The vascular disease marker CD105
2024-05-11
CD105, an endoglin, is a key endothelial cell co-receptor of the transforming growth factor-β(TGF -β) superfamily. It plays a crucial role in regulating angiogenesis and also modul...
Introduction to engineering design of recombinant antibody
2024-05-11
Since the first report of the development of monoclonal antibodies (mAbs) using hybridoma cell lines in 1975, and the approval of the first murine monoclonal antibody for human the...
A novel antibody drug conjugate targeting TROP2 has shown potent anti-tumor efficacy in breast and lung cancer
2024-05-10
BackgroundCancer is a major public health problem and the second leading cause of death worldwide, with breast and lung cancer being the two most common cancers. Despite significan...
CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses
2024-05-09
BackgroundCoronaviruses have repeatedly threatened humanity, particularly COVID-19, caused by the novel coronavirus SARS-CoV-2 (SARS-CoV-2), which poses a significant threat to glo...
Introduction to antibody structure subtype
2024-05-08
Due to their high specificity and selectivity, antibodies have always had the potential to become widely used. Over the past 40 years, they have truly revolutionized the field of b...