Regulatory target of neuronal regeneration and survival RGMA
2025-11-25
RGMA plays multiple functions in the developmental and adult nervous systems. It regulates cephalane tube closure, inhibits neurite growth and cortical neuronal branching, and prom...
Transmembrane serine threonine kinases TGFBR1 and TGFBR2
2025-11-25
Transmembrane serine/threonine kinases TGFBR1 and TGFBR2 are non-pleiotropic receptors for TGF-β cytokines (TGFB1, TGFB2, and TGFB3). They transduce TGFB1, TGFB2, and TGFB3 signals...
The target for regulating melanin production TYRP1
2025-11-24
Tyrosinase-associated protein 1 (TYPR1), also known as CAS2, TYRP, TYRRP, or TRP1, plays an important role in melanin biosynthesis and can regulate or influence the type of melanin...
The osteogenesis inhibitor SOST
2025-11-24
Sclerostin (SOST) is a negative regulator of bone growth, acting by inhibiting Wnt signaling and bone formation. SOST regulates bone metabolism and is also expressed in cardiovascu...
Oxidized low density lipoprotein receptor OLR1
2025-11-18
OLR1 is a receptor that mediates the recognition, internalization, and degradation of oxidized low-density lipoprotein (oxLDL) by vascular endothelial cells. Besides binding to oxL...
Vascular endothelial growth factor receptor VEGFR1
2025-11-17
Vascular endothelial growth factor receptor 1 (VEGFR1), also known as FLT1 or FRT, is a tyrosine protein kinase. As a cell surface receptor for VEGFA, VEGFB, and PGF, it plays a cr...
Pain treatment target NGF
2025-11-17
β-nerve growth factor (NGF), also known as NGFB, is an extracellular ligand for NTRK1 and NGFR receptors. During growth and development, NGF promotes neuronal survival, proliferati...