CD40 ligand CD154
2026-04-22
CD154, also known as CD40 ligand (CD40L), is a transmembrane glycoprotein with a trimeric structure. It belongs to the tumor necrosis factor (TNF) family and is primarily expressed...
Cytokine receptor-like factor 2
2026-04-21
Cytokine receptor-like factor 2 (CRLF2), also known as thymic stromal lymphopoietin receptor (TSLPR), is a member of the type I cytokine receptor superfamily. CRLF2 is expressed in...
ADAMTS-like protein 5
2026-04-20
ADAMTSL5 is a secreted glycoprotein belonging to the ADAMTS superfamily but lacking protease activity. It is widely expressed in various tissues, including skin and joints, serving...
Gastric mucin MUC5A
2026-04-17
Mucins are structurally classified into four classes: membrane-restricted mucins containing tandem repeat (TR) sequences, cysteine-rich secretory mucins (containing TR sequences), ...
The therapeutic target of neuralgia GFRA3
2026-04-17
The GDNF family has four members: GFRα1, GFRα2, GFRα3, and GFRα4. They are anchored to the cell membrane via extracellular vesicle anchoring structures containing extracellular ves...
Nuclear receptor subfamily 3 group C member 1
2026-04-16
The glucocorticoid receptor (GR) is a member of the nuclear receptor (NR) superfamily, subgroup 3, encoded by the NR3C1 gene, located on chromosome 5 (5q31). GR is a steroid h...
Lymphotoxin LTA
2026-04-15
LTA is a lymphotoxin, also known as tumor necrosis factor-β(TNF-β), a member of the tumor necrosis factor ligand superfamily. Lymphotoxins are produced by lymphocytes and are cytot...