The epidermal growth factor receptor ligand EREG
The epidermal growth factor receptor ligand EREG
2025-08-05
Prosecretin (EREG) is a ligand for epidermal growth factor receptor /EGFR and ERBB4. It promotes tyrosine phosphorylation of EGFR and ERBB4. It participates in inflammation, wound ...
The introduction of the Principle Procedure and Applications of MicroScale Thermophoresis（MST）
The introduction of the Principle Procedure and Applications of MicroScale Thermophoresis（MST）
2025-08-04
BackgroundMicroscale thermophoresis (MST) is a biophysical technique that measures the strength of an interaction between two molecules by detecting changes in fluorescence signal ...
The ADC target antigen TPBG
The ADC target antigen TPBG
2025-08-01
The tumor antigen 5T4/WAIF1 (Wnt activation inhibitory factor 1; also known as trophoblast glycoprotein TPBG) is a cell surface protein targeted in multiple cancer immunotherapy cl...
Tumor immunoregulatory target ITGB6
Tumor immunoregulatory target ITGB6
2025-07-31
Integrin αVβ6 (ITGAV: ITGB6) is a receptor for fibronectin and cellular actin. It recognizes the RGD sequence in its ligands. Internalization of integrin α-V/β-6 via clathrin-media...
The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
2025-07-30
Transmembrane protein with an EGF-like and two follistatin-like domains2/Tomoregulin-2 (TMEFF2) is a member of the EGF protein family. TMEFF2 is primarily expressed in the cerebral...
The target of Activin receptor type 2B ACVR2B
The target of Activin receptor type 2B ACVR2B
2025-07-30
Activin receptor type 2B serine/threonine kinase receptor (ACVR2B) is a type II transmembrane protein. ACVR2B is activin A receptor type 2B, a type II receptor serine/threonine kin...
Collagen recognizes the integrin ITGA2
Collagen recognizes the integrin ITGA2
2025-07-29
Integrin alpha-2 (ITGA2), also known as CD49b, is a key member of the integrin family. It serves as a receptor for laminin, collagen, collagen C-peptide, fibronectin, and E-cadheri...