The target of Stabilin-1/STAB1
The target of Stabilin-1/STAB1
2025-09-09
Stabilin-1(STAB1/FEEL1/KIAA0246), is a type I transmembrane protein with two main functions: “scavenger receptor function”and “cell adhesion function''. It is primarily expres...
Neurotrophic factor receptor NRP1
Neurotrophic factor receptor NRP1
2025-09-08
Neurotrophin receptor 1 (NRP1), also known as CD304, is a cell surface receptor involved in cardiovascular development, angiogenesis, the formation of certain neuronal circuits, an...
The introduction of Surface Plasmon Resonance
The introduction of Surface Plasmon Resonance
2025-09-04
BackgroundSurface plasmon resonance (SPR) is a well-established, label-free technique for directly measuring biomolecular affinity. SPR analysis requires immobilizing an interactin...
The target of Signal Regulatory Protein Alpha SIRPα
The target of Signal Regulatory Protein Alpha SIRPα
2025-09-03
Regulatory Protein Alpha ( SIRPA) is a type I transmembrane protein whose core function is to transmit the "don't eat me" signal through the SIRP A -CD47 axis, inhibiting macrophag...
The target of Sialic acid-binding Ig-like lectin 8 SIGLEC8
The target of Sialic acid-binding Ig-like lectin 8 SIGLEC8
2025-09-02
Sialic acid-binding immunoglobulin-like lectin 8 ( SIGLEC8) is a transmembrane protein that primarily functions as an inhibitory receptor, acting like a brake on the immune system....
Protein antibody SPR enabling new drug development
Protein antibody SPR enabling new drug development
2025-09-01
BackgroundThe emergence and rapid spread of multidrug-resistant Botrytis cinerea poses a significant challenge to the quality and safety of agricultural products and the efficient ...
Deep learning guided design of dynamic proteins
Deep learning guided design of dynamic proteins
2025-08-29
BackgroundDeep learning has greatly advanced the design of highly stable static protein structures. However, mimicking the controllable conformational dynamics of natural switch pr...