The osteogenesis inhibitor SOST
The osteogenesis inhibitor SOST
2025-11-24
Sclerostin (SOST) is a negative regulator of bone growth, acting by inhibiting Wnt signaling and bone formation. SOST regulates bone metabolism and is also expressed in cardiovascu...
Oxidized low density lipoprotein receptor OLR1
Oxidized low density lipoprotein receptor OLR1
2025-11-18
OLR1 is a receptor that mediates the recognition, internalization, and degradation of oxidized low-density lipoprotein (oxLDL) by vascular endothelial cells. Besides binding to oxL...
Vascular endothelial growth factor receptor VEGFR1
Vascular endothelial growth factor receptor VEGFR1
2025-11-17
Vascular endothelial growth factor receptor 1 (VEGFR1), also known as FLT1 or FRT, is a tyrosine protein kinase. As a cell surface receptor for VEGFA, VEGFB, and PGF, it plays a cr...
Pain treatment target NGF
Pain treatment target NGF
2025-11-17
β-nerve growth factor (NGF), also known as NGFB, is an extracellular ligand for NTRK1 and NGFR receptors. During growth and development, NGF promotes neuronal survival, proliferati...
The key regulator of angiogenesis RSPO3
The key regulator of angiogenesis RSPO3
2025-11-11
RSPO3, also known as PWTSR or THSD2, is a protein containing a TSP1-type repeat sequence. It acts as an activator of the canonical Wnt signaling pathway, functioning as a ligand fo...
Macrophage stimulating protein receptor MST1R
Macrophage stimulating protein receptor MST1R
2025-11-10
The macrophage-stimulating protein receptor (MST1R), also known as PTK8, RON, or CD136, is a receptor tyrosine kinase that transduces extracellular matrix signals into the cytoplas...
Human guanylate cyclase GUCY2C
Human guanylate cyclase GUCY2C
2025-11-10
Guanylate cyclase (GUCY2C), also known as GUC2C or STAR, is a guanylate cyclase that catalyzes the synthesis of cyclic guanosine monophosphate (cGMP) from GTP. It is a receptor tha...