Nervous system regulatory factor LINGO1
2026-01-26
LINGO1 belongs to the Nogo receptor complex and influences oligodendrocyte differentiation, axonal regeneration, and neuronal survival, playing a crucial role in central nervous sy...
Coagulation pathway promoter CD142
2026-01-26
Tissue factor (CD142), also known as coagulation factor III, F3, or CD142, initiates the blood clotting process by forming a complex with circulating factor VII or VIIa. The CD142/...
Emerging immune regulatory target BTN1A1
2026-01-20
BTN1A1 has been shown to inhibit T cell activation both in vitro and in vivo. Strong BTN1A1 expression was detected in a range of solid tumor tissue samples, and its expression is ...
Tumor microenvironment homeostasis regulator CLU
2026-01-19
Clusterin (CLU), also known as complement cell lysis inhibitor (CLI), apolipoprotein J (APOJ), complement-associated protein SP-40, or aging-associated gene 4 protein (AAG4), parti...
Tumor necrosis facto superfamily receptor TWEAKR
2026-01-19
Tumor necrosis factor receptor superfamily member 12A (TNFRSF12A), also known as fibroblast growth factor-induced early response protein 14 (FN14), TWEAKR, or CD266, is the TNFSF12...
The positive regulator of complement CFP
2026-01-13
CFP (Properdin) is a positive regulator of the complement alternative pathway (AP). It binds to and stabilizes the C3 and C5 convertase complex, inhibiting CFI-CFH-mediated degrada...
Carbonic anhydrase CA9
2026-01-13
Tumor hypoxia remains a significant challenge for the effective treatment of most cancers. Tumor cells in hypoxic environments often exhibit strong resistance to most treatment mod...