Cellular cytoskeleton regulatory protein VIM
Cellular cytoskeleton regulatory protein VIM
2026-01-05
Vimentin (VIM) is a cytoskeletal intermediate filament protein that controls the morphology and function of mesenchymal cells. Vimentin also participates in various cellular activi...
Wnt signaling coreceptor LGR5
Wnt signaling coreceptor LGR5
2026-01-05
Leucine-rich G protein-coupled receptor 5 (LGR5), acting as a receptor for R-vertebral proteins (RSPO1, RSPO2, RSPO3, or RSPO4), enhances the classical Wnt signaling pathway and fu...
A key regulator of the vasculature ADM
A key regulator of the vasculature ADM
2025-12-23
Adrenomedullin (ADM) is a peptide hormone and a potent vasodilator. In normal tissues, ADM plays a crucial role in regulating blood pressure, angiogenesis, and immune regulation. A...
Calcitonin gene-related peptide CGRP
Calcitonin gene-related peptide CGRP
2025-12-23
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide found in the nervous system. It is a potent vasodilator and a modulator of cerebrovascular pain. CGRP exists ...
A therapeutic antibody targeting TM4SF4 with anti-tumor activity
A therapeutic antibody targeting TM4SF4 with anti-tumor activity
2025-12-22
BackgroundTransmembrane 4 superfamily member 4 (TM4SF4) has been identified as a key regulator closely associated with stem cell characteristics related to epithelial-mesenchymal t...
Neurotensin receptor SORT1
Neurotensin receptor SORT1
2025-12-15
Neurotensin receptor 3 (NRT3), also known as glycoprotein 95 (Gp95) or sorting protein (SORT1), functions as a sorting receptor within the Golgi apparatus and a clearance receptor ...
Target for migraine treatment ADCYAP1
Target for migraine treatment ADCYAP1
2025-12-15
Pituitary adenylate cyclase activating peptide (ADCYAP1/PACAP) plays a broad and powerful physiological and pathophysiological role in the central and peripheral nervous systems. B...