The co-inhibitory immune checkpoint KLRC1
The co-inhibitory immune checkpoint KLRC1
2025-10-21
KLRC1 is an NKG2-A/NKG2-B type II integral membrane protein and an NKG2-A/B-activated natural killer receptor, also known as CD159a. Binding of CD94/NKG2A to its ligand HLA-E suppr...
The immune regulatory lectin KLRB1
The immune regulatory lectin KLRB1
2025-10-20
Killer cell lectin-like receptor subfamily B member 1 (KLRB1), also known as CD161, plays an inhibitory role in natural killer (NK) cell cytotoxicity. As a lectin, it binds to the ...
The transglutaminase TGM2
The transglutaminase TGM2
2025-10-15
Protein-glutamine gamma-glutamyltransferase 2 (TGM2) belongs to the transglutaminase family, which is ubiquitously expressed in various cell types and involved in many key cellular...
Killer cell lectin-like receptor KLRG1
Killer cell lectin-like receptor KLRG1
2025-10-14
Killer cell lectin-like receptor subfamily G member 1 (KLRG1), also known as CLEC15A, MAFA, and MAFAL, is an immune checkpoint receptor primarily expressed on natural killer (NK) a...
The cell adhesion molecule ITGB2
The cell adhesion molecule ITGB2
2025-10-13
Integrins play a crucial role in regulating the adhesion and migration of phagocytes to inflamed organs and other immune processes. ITGB2 is a component of the β2 integrin subunit,...
Sour neuronal signalling attenuates macrophage mediated liver injury
Sour neuronal signalling attenuates macrophage mediated liver injury
2025-10-11
Service SupportWe undertook the custom development of TAFA2, a key regulatory active protein in this study.(Data source: Project Development Data)BackgroundLiver damage is a c...
Optimizing the colloidal stability and viscosity of multi-specific antibodies
Optimizing the colloidal stability and viscosity of multi-specific antibodies
2025-10-10
BackgroundThe discovery and development of multispecific antibodies presents unique challenges in optimizing their physicochemical properties for developability and manufacturabili...