The target of MUC17 transmembrane mucin MUC17
The target of MUC17 transmembrane mucin MUC17
2025-07-07
Transmembrane mucins are major components of the gastric mucosal barrier, comprising a family of high-molecular-weight glycoproteins that are expressed by specialized epithelial ce...
Granulocyte colony stimulating factor receptor CSF3R
Granulocyte colony stimulating factor receptor CSF3R
2025-07-02
CSF3R is a granulocyte colony-stimulating factor receptor, also known as GCSF-R or CD114. It is essential for granulocyte maturation and plays a key role in the proliferation, diff...
The immunosuppressive enzyme CD39
The immunosuppressive enzyme CD39
2025-07-01
The ATP-adenosine pathway plays a key role in establishing an immunosuppressive tumor microenvironment (TME) by converting proinflammatory extracellular ATP into immunosuppressive ...
The therapeutic target of systemic lupus erythematosus BDCA2
The therapeutic target of systemic lupus erythematosus BDCA2
2025-06-30
CD303, also known as BDCA2, DLEC, or CLEC4C, is a unique type II C-type lectin receptor (CLR) found on human plasmacytoid dendritic cells (pDCs). It assists TLR-7/9 in recognizing ...
Bone morphogenetic protein antagonist GREM1
Bone morphogenetic protein antagonist GREM1
2025-06-27
Dysregulation of bone morphogenetic protein (BMP) signaling frequently occurs in cancer and may lead to dysregulated cancer stem cell (CSC) differentiation and promote tumorigenesi...
The myogenesis inhibitory factor MSTN
The myogenesis inhibitory factor MSTN
2025-06-24
Growth/differentiation factor 8 (GDF8), also known as myostatin (MSTN), is a specific negative regulator of skeletal muscle (SM) growth. As a member of the TGF-β family, it may be ...
Lymphocyte activation targets CD6
Lymphocyte activation targets CD6
2025-06-23
CD6 is a type I transmembrane glycoprotein that belongs to the highly conserved scavenger receptor cysteine-rich superfamily (SRCR-SF). It is expressed on all developing and mature...