Tumor immunoregulatory target ITGB6
Tumor immunoregulatory target ITGB6
2025-07-31
Integrin αVβ6 (ITGAV: ITGB6) is a receptor for fibronectin and cellular actin. It recognizes the RGD sequence in its ligands. Internalization of integrin α-V/β-6 via clathrin-media...
The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
2025-07-30
Transmembrane protein with an EGF-like and two follistatin-like domains2/Tomoregulin-2 (TMEFF2) is a member of the EGF protein family. TMEFF2 is primarily expressed in the cerebral...
The target of Activin receptor type 2B ACVR2B
The target of Activin receptor type 2B ACVR2B
2025-07-30
Activin receptor type 2B serine/threonine kinase receptor (ACVR2B) is a type II transmembrane protein. ACVR2B is activin A receptor type 2B, a type II receptor serine/threonine kin...
Collagen recognizes the integrin ITGA2
Collagen recognizes the integrin ITGA2
2025-07-29
Integrin alpha-2 (ITGA2), also known as CD49b, is a key member of the integrin family. It serves as a receptor for laminin, collagen, collagen C-peptide, fibronectin, and E-cadheri...
Apoptosis initiating receptor DR5
Apoptosis initiating receptor DR5
2025-07-25
The death receptor DR5 is a member of the tumor necrosis factor receptor superfamily, member 10B (TNFRSF10B), also known as tumor necrosis factor-related apoptosis-inducing ligand ...
Anti-Müllerian hormone receptor AMHR2
Anti-Müllerian hormone receptor AMHR2
2025-07-24
AMHR2（Anti-Müllerian hormone receptor）is a key receptor in the transforming growth factor-β (TGF-β) superfamily. In recent years, it has become a research hotspot for targeted ther...
Development and preclinical characterization of AMG 329 a human antibody neutralizing FLT3 ligand
Development and preclinical characterization of AMG 329 a human antibody neutralizing FLT3 ligand
2025-07-23
BackgroundSignaling pathways involving the receptor tyrosine kinase FLT3 and FLT3 ligand regulate the development and activity of dendritic cells (DCs) and other myeloid cells, inc...