The therapeutic target of systemic lupus erythematosus BDCA2
The therapeutic target of systemic lupus erythematosus BDCA2
2025-06-30
CD303, also known as BDCA2, DLEC, or CLEC4C, is a unique type II C-type lectin receptor (CLR) found on human plasmacytoid dendritic cells (pDCs). It assists TLR-7/9 in recognizing ...
Bone morphogenetic protein antagonist GREM1
Bone morphogenetic protein antagonist GREM1
2025-06-27
Dysregulation of bone morphogenetic protein (BMP) signaling frequently occurs in cancer and may lead to dysregulated cancer stem cell (CSC) differentiation and promote tumorigenesi...
The myogenesis inhibitory factor MSTN
The myogenesis inhibitory factor MSTN
2025-06-24
Growth/differentiation factor 8 (GDF8), also known as myostatin (MSTN), is a specific negative regulator of skeletal muscle (SM) growth. As a member of the TGF-β family, it may be ...
Lymphocyte activation targets CD6
Lymphocyte activation targets CD6
2025-06-23
CD6 is a type I transmembrane glycoprotein that belongs to the highly conserved scavenger receptor cysteine-rich superfamily (SRCR-SF). It is expressed on all developing and mature...
Multifunctional cell adhesion and signaling molecule CEACAM6
Multifunctional cell adhesion and signaling molecule CEACAM6
2025-06-18
Cell adhesion molecule 6 (CEACAM6), also known as CD66c or NCA-90, is a cell surface glycoprotein that plays a role in cell adhesion and tumor progression. CEACAM6 is commonly upre...
Activin receptor type 1 kinase ACVR1
Activin receptor type 1 kinase ACVR1
2025-06-17
Activin receptor type 1(ACVR1), also known as ALK2, is a type I receptor for bone morphogenetic protein (BMP) that is involved in multiple biological processes, including the devel...
Tyrosine protein kinase transmembrane receptor ROR2
Tyrosine protein kinase transmembrane receptor ROR2
2025-06-16
The tyrosine protein kinase transmembrane receptor ROR2 belongs to the receptor tyrosine kinase (RTK) superfamily. ROR2 is expressed during embryonic development and participates i...