The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
The target of Transmembrane protein with an EGF-like and two Follistatin-like domains2 TMEFF2
2025-07-30
Transmembrane protein with an EGF-like and two follistatin-like domains2/Tomoregulin-2 (TMEFF2) is a member of the EGF protein family. TMEFF2 is primarily expressed in the cerebral...
The target of Activin receptor type 2B ACVR2B
The target of Activin receptor type 2B ACVR2B
2025-07-30
Activin receptor type 2B serine/threonine kinase receptor (ACVR2B) is a type II transmembrane protein. ACVR2B is activin A receptor type 2B, a type II receptor serine/threonine kin...
Collagen recognizes the integrin ITGA2
Collagen recognizes the integrin ITGA2
2025-07-29
Integrin alpha-2 (ITGA2), also known as CD49b, is a key member of the integrin family. It serves as a receptor for laminin, collagen, collagen C-peptide, fibronectin, and E-cadheri...
Apoptosis initiating receptor DR5
Apoptosis initiating receptor DR5
2025-07-25
The death receptor DR5 is a member of the tumor necrosis factor receptor superfamily, member 10B (TNFRSF10B), also known as tumor necrosis factor-related apoptosis-inducing ligand ...
Anti-Müllerian hormone receptor AMHR2
Anti-Müllerian hormone receptor AMHR2
2025-07-24
AMHR2（Anti-Müllerian hormone receptor）is a key receptor in the transforming growth factor-β (TGF-β) superfamily. In recent years, it has become a research hotspot for targeted ther...
Development and preclinical characterization of AMG 329 a human antibody neutralizing FLT3 ligand
Development and preclinical characterization of AMG 329 a human antibody neutralizing FLT3 ligand
2025-07-23
BackgroundSignaling pathways involving the receptor tyrosine kinase FLT3 and FLT3 ligand regulate the development and activity of dendritic cells (DCs) and other myeloid cells, inc...
The target of Domain Containing3 LYPD3
The target of Domain Containing3 LYPD3
2025-07-23
LY6/PLAUR Domain Containing 3(LYPD3/C4.4A) is a member of the LY6/uPAR protein family. LYPD3 is expressed in the placenta, skin, and urothelium. PLAUR encodes the urokinase-type pl...