The costimulatory receptor GITR
The costimulatory receptor GITR
2025-06-10
Tumor necrosis factor receptor family member 18 (TNFRSF18), also known as GITR, is a glucocorticoid-induced TNFR-related protein and the receptor for TNFSF18. It is expressed on a ...
Anti-fibrotic target CTGF
Anti-fibrotic target CTGF
2025-06-09
CTGF is a connective tissue growth factor, also known as CCN2 or HCS24, a member of the CCN family. CTGF is a multifunctional protein secreted in various fibrous tissues and is inv...
T-cell activation regulatory factor DPP4
T-cell activation regulatory factor DPP4
2025-06-06
Dipeptidyl peptidase 4 (DPP4), also known as CD26, is a cell surface glycoprotein receptor involved in the costimulatory signaling of T cell receptor (TCR)-mediated T cell activati...
IL12B is the core component of the immune engine IL12
IL12B is the core component of the immune engine IL12
2025-06-05
IL12B , also known as IL12-p40, can act as a growth factor that activates T cells and NK cells. It can enhance the lytic activity of NK/lymphokine-activated killer cells and stimul...
A comprehensive antigen-antibody complex database unlocking insights into interaction interface
A comprehensive antigen-antibody complex database unlocking insights into interaction interface
2025-06-04
BackgroundAntibodies are essential components of the immune system and have a wide range of biomedical applications. Elucidating the complex interactions between antibodies and ant...
DKK1 is the core accomplicker of tumor immune escape
DKK1 is the core accomplicker of tumor immune escape
2025-06-02
DKK1 is a canonical Wnt signaling inhibitor that is overexpressed in many cancers and is often associated with poor clinical outcomes. DKK1 antagonizes canonical Wnt signaling by i...
Macrophage activation marker CD163
Macrophage activation marker CD163
2025-05-27
Scavenger receptor cysteine-rich type 1 protein M130 (CD163) is a macrophage-specific receptor that plays a key role in clearing hemoglobin released during hemolysis and preventing...