The folate receptor FOLR1
2025-03-24
Folate receptor α (FOLR1 / FRα) is a high-affinity folate-binding protein and one of the major folate transporters. Overexpression of FOLR1 is often associated with accelerated can...
Don't eat my signaling protein CD47
2025-03-21
The leukocyte surface antigen CD47, also known as MER6 or IAP, is a ligand for signal regulatory protein α (SIRPα). Its extracellular domain (ECD) is a cell surface self-marker tha...
Macrophage migration inhibitor MIF
2025-03-20
Macrophage migration inhibitory factor (MIF) has been discovered as an inhibitor of T lymphocyte induction and acts as a pleiotropic proinflammatory cytokine. It is involved in var...
Advancements in Escherichia coli secretion systems for enhanced recombinant protein production
2025-03-18
BackgroundEscherichia coli is one of the most studied microorganisms in microbiology. Due to its rapid growth, ease of genetic manipulation, and relatively high protein yields, it ...
Tumor immune regulator CD70
2025-03-17
CD70 is primarily expressed on B cells and is the ligand for the CD27 receptor, also known as CD27L or TNFSF7. CD27 is primarily expressed on T cells, and the CD70-CD27 signaling p...
Multiple myeloma treatment target CD138
2025-03-14
Multiple myeloma (MM) is an incurable hematologic disease characterized by the uncontrolled growth of plasma cells, primarily in the bone marrow. CD138 (Syndecan-1 or SDC1) is a tr...
Granulocyte macrophage stimulating factor CSF2
2025-03-13
Granulocyte macrophage stimulating factor (CSF2), also known as GM-CSF, is a cytokine that drives the activation of granulocytes, including neutrophils, monocytes, macrophages, and...