ZBP1 can antagonize the DNA end excision mediated by MRE11
2025-11-04
Service SupportMabnus Bio undertook the custom development of the active protein ZBP1 in this study.BackgroundGenomic instability, a hallmark of cancer, stems from defects in the D...
The biligand shared receptor OSMR
2025-11-03
The β subunit of the tumor suppressor-M receptor (OSMR) is the β subunit of the interleukin-31 receptor. It binds to IL31RA to form the IL31 receptor. Binding to IL31 activates STA...
Target for Alzheimer's disease treatment LGALS3
2025-10-30
Galectin-3 (LGALS3), also known as MAC2, Gal-3, and IgE-binding protein, participates in acute inflammatory responses, including neutrophil activation and adhesion, monocyte-macrop...
The lymphocyte antigen CD205
2025-10-29
CD205, encoded by the LY75 gene (lymphocyte antigen 75, DEC-205), is a surface polysaccharide receptor whose cytoplasmic domain contains protein motifs critical for endocytosis and...
Killer cell activation receptor KLRK1
2025-10-28
NKG2-D type II integral membrane protein (KLRK1), also known as CD314 and NKG2D, is a member of the killer cell lectin-like receptor subfamily K, member 1. As an activating and co-...
The cell adhesion molecule ALCAM
2025-10-27
ALCAM is an activated leukocyte cell adhesion molecule, also known as CD166 and MEMD , mediating heterotypic cell contacts and homotypic cell contacts through its interaction ...
The co-inhibitory immune checkpoint KLRC1
2025-10-21
KLRC1 is an NKG2-A/NKG2-B type II integral membrane protein and an NKG2-A/B-activated natural killer receptor, also known as CD159a. Binding of CD94/NKG2A to its ligand HLA-E suppr...