The ammonia produced by tumors promotes the enrichment of regulatory T-cells and inhibits the anti-tumor immune response
The ammonia produced by tumors promotes the enrichment of regulatory T-cells and inhibits the anti-tumor immune response
2026-01-06
Service SupportMabnus Biotech provided services for recombinant protein expression, molecular docking kinetics simulation, and SPR affinity detection in this study.BackgroundRegula...
Cellular cytoskeleton regulatory protein VIM
Cellular cytoskeleton regulatory protein VIM
2026-01-05
Vimentin (VIM) is a cytoskeletal intermediate filament protein that controls the morphology and function of mesenchymal cells. Vimentin also participates in various cellular activi...
Wnt signaling coreceptor LGR5
Wnt signaling coreceptor LGR5
2026-01-05
Leucine-rich G protein-coupled receptor 5 (LGR5), acting as a receptor for R-vertebral proteins (RSPO1, RSPO2, RSPO3, or RSPO4), enhances the classical Wnt signaling pathway and fu...
A key regulator of the vasculature ADM
A key regulator of the vasculature ADM
2025-12-23
Adrenomedullin (ADM) is a peptide hormone and a potent vasodilator. In normal tissues, ADM plays a crucial role in regulating blood pressure, angiogenesis, and immune regulation. A...
Calcitonin gene-related peptide CGRP
Calcitonin gene-related peptide CGRP
2025-12-23
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide found in the nervous system. It is a potent vasodilator and a modulator of cerebrovascular pain. CGRP exists ...
A therapeutic antibody targeting TM4SF4 with anti-tumor activity
A therapeutic antibody targeting TM4SF4 with anti-tumor activity
2025-12-22
BackgroundTransmembrane 4 superfamily member 4 (TM4SF4) has been identified as a key regulator closely associated with stem cell characteristics related to epithelial-mesenchymal t...
Neurotensin receptor SORT1
Neurotensin receptor SORT1
2025-12-15
Neurotensin receptor 3 (NRT3), also known as glycoprotein 95 (Gp95) or sorting protein (SORT1), functions as a sorting receptor within the Golgi apparatus and a clearance receptor ...