Vascular development regulatory factor ACVRL1
2026-02-24
ACVRL1 is a type I receptor for the TGF-β family ligands BMP9/GDF2 and BMP10, and is an important regulator of normal angiogenesis. It activates the downstream Smad1/5/8 signaling ...
Von Willebrand factor VWF
2026-02-24
Von von Willebrand factor (VWF) is the largest known polysaccharide protein in the blood, controlling platelet adhesion and aggregation. Its normal function requires the assembly o...
Optimization of antibody high-throughput production in CHO cells by regulating heavy and light chain promoters
2026-02-03
BackgroundOver the past decade, the number of non-natural monoclonal antibodies has grown exponentially, thanks to the emergence of bispecific and multispecific antibodies. This di...
Coagulation factor F11
2026-02-02
Coagulation factor XI (F11), also known as plasma prothrombin (PTA), or FXI, is a serine protease primarily synthesized in the liver, with lower rates of production in the pancreas...
Leukemia inhibitory factor LIF
2026-02-02
Leukemia inhibitory factor (LIF), also known as differentiation-stimulating factor or melanoma-derived LPL inhibitor (MLPLI), is a pleiotropic protein belonging to the interleukin-...
Angiogenesis regulatory target TNC
2026-01-27
Tenascin (TNC) is a cytosmal matrix-rich glycoprotein. Extracellular matrix proteins participate in guiding neuronal and axonal migration during development and are also associated...
Nervous system regulatory factor LINGO1
2026-01-26
LINGO1 belongs to the Nogo receptor complex and influences oligodendrocyte differentiation, axonal regeneration, and neuronal survival, playing a crucial role in central nervous sy...