Dendritic spine morphological regulator BAIAP2
2025-12-08
BAIAP2 is an adaptor protein, also known as FLAF3 or IRSp53; it connects membrane-bound small G proteins to cytoplasmic effector proteins. It is essential for CDC42-mediated actin ...
The Wnt pathway activates the receptor family FZD
2025-12-02
The FZD receptor family consists of seven transmembrane receptors, structurally belonging to the G protein-coupled receptor (GPCR) superfamily, but their signal transduction mechan...
The tyrosine protein kinase PDGFRA
2025-12-01
Platelet-derived growth factor receptor α (PDGFRA), also known as CD140a, is a tyrosine protein kinase (TK) that acts as the cell surface receptor for PDGFA, PDGFB, and PDGFC, play...
Regulatory T-cell activation regulatory receptor LRRC32
2025-12-01
Glycoprotein-A repetitions predominant (GARP), also known as LRRC32, is a potential docking receptor for transforming growth factor β1 (LTGF-β1) and is expressed on the surface of ...
Regulatory target of neuronal regeneration and survival RGMA
2025-11-25
RGMA plays multiple functions in the developmental and adult nervous systems. It regulates cephalane tube closure, inhibits neurite growth and cortical neuronal branching, and prom...
Transmembrane serine threonine kinases TGFBR1 and TGFBR2
2025-11-25
Transmembrane serine/threonine kinases TGFBR1 and TGFBR2 are non-pleiotropic receptors for TGF-β cytokines (TGFB1, TGFB2, and TGFB3). They transduce TGFB1, TGFB2, and TGFB3 signals...
The target for regulating melanin production TYRP1
2025-11-24
Tyrosinase-associated protein 1 (TYPR1), also known as CAS2, TYRP, TYRRP, or TRP1, plays an important role in melanin biosynthesis and can regulate or influence the type of melanin...