The chemokine CXCL10
The chemokine CXCL10
2025-09-19
Inflammatory chemokines CXCLs (CXCL9, CXCL10, CXCL11, etc.) are primarily induced by interferon (IFN)-γ and share a dedicated chemokine receptor, CXC chemokine receptor 3 (CXCR3). ...
Lectin pathway related serine protease MASP
Lectin pathway related serine protease MASP
2025-09-18
The complement system is an important component of innate immunity and can be activated through three pathways: the classical pathway (CP), the alternative pathway (AP), and the le...
Matrix metalloproteinase MMP9
Matrix metalloproteinase MMP9
2025-09-17
Matrix metalloproteinase-9 (MMP9) can specifically degrade type IV collagen and plays an important role in local proteolysis of the extracellular matrix and leukocyte migration. Du...
Prolactin receptor PRLR
Prolactin receptor PRLR
2025-09-16
Prolactin receptor (PRLR) acts as a pro-survival factor on sperm by inhibiting sperm maturation by inhibiting SRC kinase activation and stimulating AKT. PRL/PRLR signaling promotes...
C5 The target of the complement system
C5 The target of the complement system
2025-09-15
The complement system consists of a series of plasma protein interactions that directly attack pathogens and trigger inflammation. Most complement proteins are zymogens that, when ...
The target of Solute Carrier Family 1 Member 5 SLC1A5
The target of Solute Carrier Family 1 Member 5 SLC1A5
2025-09-11
Solute Carrier Family 1 Member 5 (SLC1A5/ASCT2) is a transmembrane protein that functions as a sodium-dependent neutral amino acid transporter. Encoded by the SLC1A5 gene...
Parkinson's disease treatment target SNCA
Parkinson's disease treatment target SNCA
2025-09-10
Alpha-synuclein (SNCA) is a neuronal protein that plays multiple roles in synaptic activity, including regulating synaptic vesicle trafficking and subsequent neurotransmitter relea...