FGF1: an antidiabetic potential drug target
FGF1: an antidiabetic potential drug target
2023-02-02
Fibroblast growth factor 1 ( FGF1 ) was discovered in 1979, and its molecular identity and properties were determined over the next decade. A series of studies beginning in 1989 li...
FGF19：Clinical value to be exploited
FGF19：Clinical value to be exploited
2023-02-02
The fibroblast growth factor 19 (FGF19) subfamily includes three proteins: FGF19, FGF21, and FGF23, which show activity on FGFR1c, 2c, 3c, and 4 receptors, but cannot bind to FGFR1...
FGF2: A myriad factor
FGF2: A myriad factor
2023-02-02
Fibroblast growth factor 2 (FGF2), also known as basic FGF (bFGF), is one of the earliest recognized members of the FGF family. As a ligand for FGFR1, FGFR2, FGFR3, and FGFR4, it p...
FGF20：more research attention
FGF20：more research attention
2023-02-02
Fibroblast growth factor 20 (FGF20), a member of the FGF9 subfamily, acts as a neurotrophic factor that regulates central nervous system development and function.(Data source: Alph...
FGF3: Regulation of embryonic ear development
FGF3: Regulation of embryonic ear development
2023-02-02
(Data source: AlphaFold)Fibroblast growth factor 3 (FGF3) is composed of 239 amino acids and is a secreted extracellular protein. The main functional domain is the 18-239 segment, ...
FGF21：metabolic messenger
FGF21：metabolic messenger
2023-02-02
Fibroblast growth factor 21 (FGF21) belongs to the FGF19 subfamily. It is mainly expressed in the liver and acts on adipose, liver and pancreatic tissues to regulate the metabolism...
FGF4: a potential target for lowering glucose
FGF4: a potential target for lowering glucose
2023-02-02
Fibroblast growth factor 4 (FGF4), also known as Kaposi's sarcoma FGF, plays an important role in the regulation of embryonic development, cell proliferation, and cell differentiat...