Potential tumor therapeutic target CD25
Potential tumor therapeutic target CD25
2024-03-21
The interleukin-2 receptor (IL-2R) is composed of three subunits: α (IL-2Rα , CD25), β (IL-2Rβ, CD122), and γ common (IL-2Rγ, CD132). CD25 is the only subunit of the IL-2 receptor ...
Anaphylaxis regulatory receptor CD23
Anaphylaxis regulatory receptor CD23
2024-03-21
CD23 is a low-affinity IgE receptor that plays a crucial role in regulating IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and pre...
ADCC effect factor CD16
ADCC effect factor CD16
2024-03-20
In recent years, tumor immunotherapy, particularly anti-immune checkpoint antibody therapy and CAR-T therapy, has achieved remarkable clinical success. Natural killer (NK) cells, a...
CD19 CD20 antibody fusion IL-15 protein dual targeted therapy for B-cell malignancies
CD19 CD20 antibody fusion IL-15 protein dual targeted therapy for B-cell malignancies
2024-03-13
Background:Despite the progress made in cancer therapy with monoclonal antibodies, such as the CD20 antibody rituximab, there remains a pressing need to optimize the ability of suc...
CD14: The pattern recognition receptor for LPS
CD14: The pattern recognition receptor for LPS
2024-03-13
CD14 is best known as a pattern recognition receptor of the innate immune system, where it plays an important role in sensitizing cells to Gram-negative bacterial lipopolysaccharid...
Antibody engineering series bispecific antibody
Antibody engineering series bispecific antibody
2024-03-13
Background:Bispecific antibodies (BsAbs) recognize two distinct epitopes or antigens, targeting different targets in different molecular formats and mediating anti-cancer effects t...
Polyhedral aminopeptidase CD13
Polyhedral aminopeptidase CD13
2024-03-05
CD13 (aminopeptidase N, membrane alanyl aminopeptidase, APN, EC 3.4.11.2, and ANPEP) is a ubiquitously expressed protease with multiple functions. As an enzyme, CD13 regulates the ...