Strategies to overcome the challenges of low or no expression of heterologous proteins in Escherichia coli
Strategies to overcome the challenges of low or no expression of heterologous proteins in Escherichia coli
2024-08-07
BackgroundProtein expression is a critical process in a wide range of biological systems. Escherichia coli, a microbial host widely used in industrial catalysis and healthcare, oft...
Proinflammatory cytokine IL-11
Proinflammatory cytokine IL-11
2024-08-06
Interleukin IL11 is a member of the IL-6 cytokine family. IL11 is involved in hematopoiesis and works synergistically with other cytokines to promote bone marrow hematopoiesis, meg...
Clinical validation of Fc mutations can adjust the high viscosity of IgG1 antibodies
Clinical validation of Fc mutations can adjust the high viscosity of IgG1 antibodies
2024-08-06
BackgroundOver the past few decades, antibody therapies have become increasingly common in the treatment of a variety of diseases, including cancer, inflammatory diseases, and auto...
The alarm cytokine IL-33
The alarm cytokine IL-33
2024-08-05
IL33 is a member of the IL-1 family and a ligand for the orphan receptor ST2 (also known as IL-1RL1). It plays a key role in innate and adaptive immunity, contributing to tissue ho...
Integrin alpha CD51
Integrin alpha CD51
2024-07-26
CD51, also known as integrin αV (ITGAV), can form heterodimers with β1, β3, β5, β6 and β8, respectively, to form Alpha V integrins, which play various physiological roles in tumor ...
Stimulate receptor molecules CD40
Stimulate receptor molecules CD40
2024-07-24
CD40 is a co-stimulatory receptor molecule, tumor necrosis factor receptor superfamily member 5 (TNFRSF5), whose ligand is CD40L. The CD40-CD40L interaction plays a key role in act...
Interleukin IL13
Interleukin IL13
2024-07-22
IL13 is interleukin 13, a pleiotropic cytokine that is mainly secreted by activated TH2 cells. IL13 plays a key role in diseases such as asthma, dermatitis, and cancer.IL13 product...