Macrophage colony stimulating factor 1 receptor CD115
2024-05-14
CD115 is a member of the macrophage colony-stimulating factor 1 receptor (CSF1R), also known as FMS kinase. It belongs to the protein tyrosine kinase family and the platelet-derive...
The vascular disease marker CD105
2024-05-11
CD105, an endoglin, is a key endothelial cell co-receptor of the transforming growth factor-β(TGF -β) superfamily. It plays a crucial role in regulating angiogenesis and also modul...
Introduction to engineering design of recombinant antibody
2024-05-11
Since the first report of the development of monoclonal antibodies (mAbs) using hybridoma cell lines in 1975, and the approval of the first murine monoclonal antibody for human the...
A novel antibody drug conjugate targeting TROP2 has shown potent anti-tumor efficacy in breast and lung cancer
2024-05-10
BackgroundCancer is a major public health problem and the second leading cause of death worldwide, with breast and lung cancer being the two most common cancers. Despite significan...
CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses
2024-05-09
BackgroundCoronaviruses have repeatedly threatened humanity, particularly COVID-19, caused by the novel coronavirus SARS-CoV-2 (SARS-CoV-2), which poses a significant threat to glo...
Introduction to antibody structure subtype
2024-05-08
Due to their high specificity and selectivity, antibodies have always had the potential to become widely used. Over the past 40 years, they have truly revolutionized the field of b...
CD79 is a therapeutic target for B-cell lymphoma
2024-05-07
CD79 is a transmembrane protein that binds to the B cell receptor (BCR) to form a complex and generate signals upon antigen recognition by the BCR. CD79 is composed of two distinct...