Eosinophilic inflammatory factor IL-5
2024-02-23
IL5 is mainly secreted and expressed by T2 lymphocytes Th2, innate lymphocytes ILC2, mast cells and eosinophils. These cells release IL5 after being activated by various environmen...
Allergic response regulator IL-4
2024-02-17
IL4 is a multifunctional cytokine produced by T h2 helper T cells, fibroblasts, mast cells, basophils, eosinophils, adipocytes, and a wide range of epithelial cells. IL4 acts on a ...
Immunosuppressive therapy target CD2
2024-02-17
CD2 is a transmembrane glycoprotein and one of the earliest T cell markers. It is widely expressed on the surface of human immune cells, including T cells, natural killer cells (NK...
Fc engineering modification for regulating antibody function
2024-01-23
For general detection antibodies, we mainly consider their specificity and affinity, but for functional therapeutic antibodies, in addition to these two indicators, we also need to...
The lipid antigen presenting molecule CD1a
2024-01-17
CD1a is a transmembrane protein that belongs to the CD1 family and plays an important role in the immune system. The CD1 family includes CD1a, CD1b, CD1c, and CD1d, which are close...
Inflammatory cytokine IL1β
2024-01-17
Interleukin-1 (IL-1) is a central mediator of innate immunity and inflammation. The IL-1 family includes seven agonistic ligands (IL-1a and IL-1β, IL-18, IL-33, IL-36A, and IL-36T)...
Characterization of neutralizing antibodies of broad spectrum glutenopeptide HLA-DQ2.5 complex
2024-01-04
Celiac disease (CeD), also known as gluten-sensitive enteropathy, is an autoimmune disease of the small intestine associated with the ingestion of gluten. Gluten is present in food...