Prostate cancer biomarker PSA
Prostate cancer biomarker PSA
2024-06-21
Prostate-specific antigen (PSA) is a single-chain glycoprotein also known as γ-semioplasmin or kallikrein-3 (KLK3). PSA in blood exists in both free (f) and complexed (c) forms and...
The sepsis biomarker PCT
The sepsis biomarker PCT
2024-06-20
Procalcitonin (PCT) is a hormonally inactive precursor of calcitonin that possesses secondary inflammatory, chemokine, anti-inflammatory, and protective properties. Procalcitonin p...
Sensitive inflammatory markers SAA
Sensitive inflammatory markers SAA
2024-06-19
Serum amyloid A (SAA) is a nonspecific acute phase protein primarily produced by liver cells. It acts as an immune preventive molecule, combating local inflammatory damage. When in...
Broad spectrum tumor markers CEA
Broad spectrum tumor markers CEA
2024-06-18
Carcinoembryonic antigen (CEA) is a complex acidic glycoprotein. CEA belongs to the immunoglobulin family known as CEA-related cell adhesion molecules (CEACaMs), also known as CEAC...
The inflammatory marker CRP
The inflammatory marker CRP
2024-06-15
C-reactive protein (CRP), a biomarker of inflammation, is an acute-phase protein primarily synthesized in the liver in response to various inflammatory stimuli. CRP is composed of ...
The heart failure marker ST2
The heart failure marker ST2
2024-06-14
ST2, short for growth stimulation expressed gene 2 (ST2), also known as Suppression of Tumorigenicity 2, is a member of the interleukin-1 receptor family and was formerly known as ...
Development and characterization of a pharmacokinetics (PK) assay for T-cell involved bispecific antibody cibisatamab
Development and characterization of a pharmacokinetics (PK) assay for T-cell involved bispecific antibody cibisatamab
2024-06-13
BackgroundAppropriately designed pharmacokinetic (PK) assays that are sensitive to the effects of antidrug antibodies (ADAs) on relevant exposures are an alternative strategy for u...