Pathological study of anti-human LILRB4 antibody in a mouse model of Alzheimer's disease
Pathological study of anti-human LILRB4 antibody in a mouse model of Alzheimer's disease
2024-04-26
Background:Alzheimer's disease (AD) is the most common neurodegenerative disease in the elderly, leading to progressive cognitive impairment and ultimately death. AD pathological h...
Blood cancer therapeutic target CD45
Blood cancer therapeutic target CD45
2024-04-25
CD45 is a receptor-type tyrosine protein phosphatase C (PTPRC), also known as leukocyte common antigen (LCA). It is a type I transmembrane glycoprotein expressed on almost all hema...
The membrane attack complex inhibitor CD59
The membrane attack complex inhibitor CD59
2024-04-25
CD59 is a membrane-bound protein that functions as a membrane attack complex inhibitory factor (MACIF). It acts by binding to C8 and C9 complement components of the membrane attack...
The complement inhibitor CD55
The complement inhibitor CD55
2024-04-24
Previously, we introduced the regulatory protein CD35 (CR1) in the complement system. In this issue, we will introduce another complement system regulatory protein CD55. CD55 is th...
Therapeutic target for multiple myeloma CD38
Therapeutic target for multiple myeloma CD38
2024-04-24
CD38 is a transmembrane glycoprotein with exoenzyme activity that also functions as a receptor and adhesion molecule. CD38 is expressed at low levels in normal lymphocytes, myeloid...
Detection of small molecule ethylpyrimol residues in agricultural products and environment
Detection of small molecule ethylpyrimol residues in agricultural products and environment
2024-04-24
Background:Ethylpyrimidine, a typical pyrimidine fungicide, has been widely used for over 50 years to control powdery mildew on various fruits and vegetables. Excessive use of ethy...
Functional IgG-like stability and pharmacological studies of tetravalent bispecific antibodies
Functional IgG-like stability and pharmacological studies of tetravalent bispecific antibodies
2024-04-23
BackgroundBispecific antibodies (bsAbs) are a promising drug modality that can simultaneously bind to two distinct epitopes on the same or different antigens. So far, 14 bsAb drugs...