CovEpiAb: a comprehensive database and analysis resource for immune epitopes and antibodies of human coronaviruses
2024-05-09
BackgroundCoronaviruses have repeatedly threatened humanity, particularly COVID-19, caused by the novel coronavirus SARS-CoV-2 (SARS-CoV-2), which poses a significant threat to glo...
Introduction to antibody structure subtype
2024-05-08
Due to their high specificity and selectivity, antibodies have always had the potential to become widely used. Over the past 40 years, they have truly revolutionized the field of b...
CD79 is a therapeutic target for B-cell lymphoma
2024-05-07
CD79 is a transmembrane protein that binds to the B cell receptor (BCR) to form a complex and generate signals upon antigen recognition by the BCR. CD79 is composed of two distinct...
The adhesion molecule CD62
2024-04-29
CD62 selectins are a family of adhesion molecules consisting of L-selectin (CD62L), P-selectin (CD62P), and E-selectin (CD62E). They play important roles in immune and inflammatory...
The transferrin receptor CD71
2024-04-29
CD71 is the iron transferrin receptor 1 (TFRC), the major cell surface iron uptake protein. Iron uptake is mediated by the internalization of the transferrin (Tf)-iron complex thro...
Structure and function of therapeutic antibodies approved by the FDA in 2023
2024-04-28
BackgroundOver the past decade, the number of new antibody-based biologics approved each year has increased significantly, with the FDA approving 100 new antibodies in the past dec...
Natural killer cells typing marker CD56
2024-04-26
CD56 is a neural cell adhesion molecule (NCAM) involved in processes such as neuronal adhesion, neurite bundling, and neurite outgrowth. CD56 is a typical phenotypic marker of natu...