CD33 is a potential therapeutic target
CD33 is a potential therapeutic target
2024-04-16
CD33 is a cell surface protein belonging to the sialic acid-binding immunoglobulin-like lectins (Siglecs) family. It is a transmembrane protein that plays an important role in medi...
The complement receptor CD35
The complement receptor CD35
2024-04-15
CD35, also known as complement receptor 1 (CR1), plays a crucial role in the complement system. The complement system is part of the immune system and, through a series of cascades...
Potential tumor therapeutic target CD25
Potential tumor therapeutic target CD25
2024-03-21
The interleukin-2 receptor (IL-2R) is composed of three subunits: α (IL-2Rα , CD25), β (IL-2Rβ, CD122), and γ common (IL-2Rγ, CD132). CD25 is the only subunit of the IL-2 receptor ...
Anaphylaxis regulatory receptor CD23
Anaphylaxis regulatory receptor CD23
2024-03-21
CD23 is a low-affinity IgE receptor that plays a crucial role in regulating IgE production and B cell differentiation. On B cells, it initiates IgE-dependent antigen uptake and pre...
ADCC effect factor CD16
ADCC effect factor CD16
2024-03-20
In recent years, tumor immunotherapy, particularly anti-immune checkpoint antibody therapy and CAR-T therapy, has achieved remarkable clinical success. Natural killer (NK) cells, a...
CD19 CD20 antibody fusion IL-15 protein dual targeted therapy for B-cell malignancies
CD19 CD20 antibody fusion IL-15 protein dual targeted therapy for B-cell malignancies
2024-03-13
Background:Despite the progress made in cancer therapy with monoclonal antibodies, such as the CD20 antibody rituximab, there remains a pressing need to optimize the ability of suc...
CD14: The pattern recognition receptor for LPS
CD14: The pattern recognition receptor for LPS
2024-03-13
CD14 is best known as a pattern recognition receptor of the innate immune system, where it plays an important role in sensitizing cells to Gram-negative bacterial lipopolysaccharid...