Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila
Lsp2 links mTORC1 to TOP mRNA translation and lifespan in Drosophila
2026-10-14
On September 23, 2026, Zongzhao Zhai (Hunan Normal University) and Yirong Wang and Jiongming Lu (Hunan University)—serving as co-corresponding authors—along with co-first authors Ju...
Therapeutic Target for Itching and Inflammatory Diseases IL31RA
Therapeutic Target for Itching and Inflammatory Diseases IL31RA
2026-10-13
Interleukin-31 receptor subunit α (IL31RA), also known as cytokine receptor-like 3, Gp130-like monocyte receptor (GLM-R), CRL3, or GPL, forms a heterodimeric receptor complex with O...
Complement cascade amplification initiation enzyme C2
Complement cascade amplification initiation enzyme C2
2026-10-12
Complement C2 is a precursor to the C3 and C5 convertase complex catalytic component of the complement pathway. Component C2 is part of the classical, lectin, and GZMK complement sy...
The bidirectional signaling integrin ITGA5B1
The bidirectional signaling integrin ITGA5B1
2026-09-29
Integrin α5β1 (ITGA5B1) is a key signaling protein between cells and the extracellular matrix, formed by the nonvalent binding of the α5 subunit (ITGA5, CD49e) and the β1 subunit (I...
Tumor specific glycolipid antigen NeuGcGM3
Tumor specific glycolipid antigen NeuGcGM3
2026-09-28
Mannoceramide GM3 is a fundamental glycolipid on the surface of mammalian cells and a key regulator of transmembrane signaling and cell recognition. In oncology, GM3 exerts its tumo...
The tumor associated glycoprotein TAG-72
The tumor associated glycoprotein TAG-72
2026-09-22
TAG-72 is a tumor-associated glycoprotein, first discovered in 1981 through binding to the murine antibody B72.3, which recognizes the epitope NeuAc2-6aGalNAcal-0-Ser/Thr (STn). Als...
Killer cell immunoglobulin like receptor KIR2D
Killer cell immunoglobulin like receptor KIR2D
2026-09-21
KIR2D is a member of the killer cell immunoglobulin-like receptor (KIR) family, possessing two extracellular immunoglobulin-like domains (D1 and D2), and is primarily expressed on t...