Overview of methods used in the study of protein protein interactions
2024-11-15
Protein-protein interactions are fundamental to cellular structure and function. Most proteins do not function in isolation but rather through interactions with other proteins. The...
Overview of the research methods of protein small molecule interactions
2024-11-14
Protein-small molecule interactions play a crucial role in drug development, being central to drug mechanisms of action. With the advancement of medicinal chemistry and molecular b...
STEAP1 is a therapeutic target for prostate cancer
2024-11-12
Six-transmembrane epithelial antigen of the prostate (STEAP1) belongs to the STEAP family, which consists of four members: STEAP1, STEAP2, STEAP3, and STEAP4. First discovered in a...
NPR1 is a therapeutic target for heart failure
2024-11-11
The atrial natriuretic peptide receptor (NPR1), also known as NPRA or guanylate cyclase A (GC-A), is the receptor for atrial natriuretic peptides NPPA/ANP and brain natriuretic pep...
Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherichia coli Sepsis by Precise Periplasmic EcDsbA Targeting
2024-11-08
The Beijing Institute of Pharmacology and Toxicology recently published a research paper titled "Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherich...
SpyTag-SpyCatcher system: Protein covalent coupling technology
2024-11-07
At the forefront of biomedical research and clinical applications, protein engineering and biomolecular labeling technologies are playing a vital role. However, traditional protein...
Pathogen sensor TLR2
2024-11-05
TLR2, also known as Toll-like receptor 2 (TLR2), also known as CD282, is a pattern recognition receptor (PRR). TLR2 plays a crucial role in recognizing pathogen-associated molecula...