Tumor immune regulator CD70
Tumor immune regulator CD70
2025-03-17
CD70 is primarily expressed on B cells and is the ligand for the CD27 receptor, also known as CD27L or TNFSF7. CD27 is primarily expressed on T cells, and the CD70-CD27 signaling p...
Multiple myeloma treatment target CD138
Multiple myeloma treatment target CD138
2025-03-14
Multiple myeloma (MM) is an incurable hematologic disease characterized by the uncontrolled growth of plasma cells, primarily in the bone marrow. CD138 (Syndecan-1 or SDC1) is a tr...
Granulocyte macrophage stimulating factor CSF2
Granulocyte macrophage stimulating factor CSF2
2025-03-13
Granulocyte macrophage stimulating factor (CSF2), also known as GM-CSF, is a cytokine that drives the activation of granulocytes, including neutrophils, monocytes, macrophages, and...
The chemokine receptor CXCR4
The chemokine receptor CXCR4
2025-03-12
CXCR4, also known as CD184, is a CXC chemokine receptor type 4, a class A G protein-coupled receptor (GPCR). It is activated by chemotactic ligands and participates in regulating h...
Immune Sentinel TLR4
Immune Sentinel TLR4
2025-03-11
Toll-like receptor 4 (TLR4) is a transmembrane receptor that plays a key role in the innate immune system. It recognizes pathogen-associated molecular patterns (PAMPs) and damage-a...
YAbS: The Antibody Society's antibody therapeutics database
YAbS: The Antibody Society's antibody therapeutics database
2025-03-10
BackgroundTherapeutic antibodies have garnered significant attention in recent years for their precise ability to target specific diseases. As these molecules become increasingly i...
The pleiotropic cytokine IL9
The pleiotropic cytokine IL9
2025-03-07
Interleukin 19 (IL19), a member of the IL-2RγC chain family, is a pleiotropic cytokine that regulates the functions of various cells. Originally identified as a growth factor for T...