Overview of the research methods of protein small molecule interactions
Overview of the research methods of protein small molecule interactions
2024-11-14
Protein-small molecule interactions play a crucial role in drug development, being central to drug mechanisms of action. With the advancement of medicinal chemistry and molecular b...
STEAP1 is a therapeutic target for prostate cancer
STEAP1 is a therapeutic target for prostate cancer
2024-11-12
Six-transmembrane epithelial antigen of the prostate (STEAP1) belongs to the STEAP family, which consists of four members: STEAP1, STEAP2, STEAP3, and STEAP4. First discovered in a...
NPR1 is a therapeutic target for heart failure
NPR1 is a therapeutic target for heart failure
2024-11-11
The atrial natriuretic peptide receptor (NPR1), also known as NPRA or guanylate cyclase A (GC-A), is the receptor for atrial natriuretic peptides NPPA/ANP and brain natriuretic pep...
Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherichia coli Sepsis by Precise Periplasmic EcDsbA Targeting
Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherichia coli Sepsis by Precise Periplasmic EcDsbA Targeting
2024-11-08
The Beijing Institute of Pharmacology and Toxicology recently published a research paper titled "Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherich...
SpyTag-SpyCatcher system: Protein covalent coupling technology
SpyTag-SpyCatcher system: Protein covalent coupling technology
2024-11-07
At the forefront of biomedical research and clinical applications, protein engineering and biomolecular labeling technologies are playing a vital role. However, traditional protein...
Pathogen sensor TLR2
Pathogen sensor TLR2
2024-11-05
TLR2, also known as Toll-like receptor 2 (TLR2), also known as CD282, is a pattern recognition receptor (PRR). TLR2 plays a crucial role in recognizing pathogen-associated molecula...
Skin inflammation treatment target IL36R
Skin inflammation treatment target IL36R
2024-11-04
IL-36 belongs to the IL-1 superfamily of cytokines and is composed of three agonists (IL-36α, IL-36β, and IL-36γ) and one antagonist (IL-36Ra). IL-36R, also known as IL1RL2, IL-1Rr...