Consideration of recombinant expression of His small label fusion protein
Consideration of recombinant expression of His small label fusion protein
2025-01-03
BackgroundThe Histidine tag (polyhistidine tag) is a commonly used protein tag used for protein expression, purification, and detection in biochemistry and molecular biology. It co...
T-cell costimulatory molecule OX40
T-cell costimulatory molecule OX40
2025-01-02
OX40 is a T cell co-stimulatory molecule and a member of the tumor necrosis factor receptor superfamily member 4 (TNFRSF4), also known as CD134. OX40 plays a crucial co-stimulatory...
Trophoblast cell surface antigen TROP2
Trophoblast cell surface antigen TROP2
2024-12-31
Trophoblast cell surface antigen 2 (TROP2), also known as tumor-associated calcium signal sensor 2 (TACSTD2), is overexpressed in a range of solid tumors and significantly impacts ...
Tissue factor pathway inhibitor TFPI
Tissue factor pathway inhibitor TFPI
2024-12-30
Tissue factor pathway inhibitor ( TFPI ) is an alternatively spliced anticoagulant protein that primarily inhibits the initial stage of coagulation, preceding thrombin generation. ...
Advancements and challenges in immunocytokines
Advancements and challenges in immunocytokines
2024-12-27
BackgroundImmunocytokines utilize targeted antibodies to concentrate cytokines at tumor sites and have shown potential advantages, such as prolonged cytokine half-life, reduced adv...
The angiogenin VEGFA
The angiogenin VEGFA
2024-12-25
Vascular endothelial growth factor (VEGF) is a homodimeric vasoactive glycoprotein and a key mediator of angiogenesis. The VEGF family consists of five separate gene products: VEGF...
The immunosuppressive molecule B7H4
The immunosuppressive molecule B7H4
2024-12-23
B7H4, V-set domain-containing inhibitor of T-cell activation 1 (VTCN1), also known as B7x, is a member of the B7 family and an inhibitory immune checkpoint. It negatively regulates...