Suitable conditions were selected for eukaryotic protein expression
Suitable conditions were selected for eukaryotic protein expression
2024-09-09
Eukaryotic mammalian expression systems play a crucial role in protein expression technology. Mammalian protein production has become the standard for the production of state-of-th...
Immune stimulation of the cytokine IL-21
Immune stimulation of the cytokine IL-21
2024-09-05
Interleukin-21 (IL-21) is an immunostimulatory cytokine that belongs to the common gamma-chain cytokine family. It plays an important role in the development, differentiation, prol...
Novel immunotherapeutics against LGR5 to target multiple cancer types
Novel immunotherapeutics against LGR5 to target multiple cancer types
2024-09-04
BackgroundLeucine-rich repeat-containing G protein receptor 5 (LGR5) is a target gene of the oncogenic Wnt signaling pathway in colorectal cancer cells. LGR5 is overexpressed in hu...
Neonatal Fc receptor FcRn
Neonatal Fc receptor FcRn
2024-09-03
The neonatal Fc receptor (FcRn) binds to the Fc portion of IgG in a pH-dependent manner, protecting it from intracellular degradation. FcRn not only protects IgG but also participa...
B-cell activating factor BAFF
B-cell activating factor BAFF
2024-09-02
BAFF is a B cell-activating factor and a member of the tumor necrosis factor ligand superfamily, member 13B (TNFSF13B, CD57), also known as BLyS. It is a ligand for three receptors...
Human epidermal growth factor receptor HER2
Human epidermal growth factor receptor HER2
2024-08-30
HER2, also known as human epidermal growth factor receptor 2 (ERBB2), plays a crucial role in cell proliferation, survival, and differentiation. HER2 is a key target for the treatm...
Receptor tyrosine kinase-like orphan receptor ROR1
Receptor tyrosine kinase-like orphan receptor ROR1
2024-08-29
Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is lowly expressed or absent in normal tissues, but its expression is significantly elevated in a variety of malignancies and...