NPR1 is a therapeutic target for heart failure
2024-11-11
The atrial natriuretic peptide receptor (NPR1), also known as NPRA or guanylate cyclase A (GC-A), is the receptor for atrial natriuretic peptides NPPA/ANP and brain natriuretic pep...
Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherichia coli Sepsis by Precise Periplasmic EcDsbA Targeting
2024-11-08
The Beijing Institute of Pharmacology and Toxicology recently published a research paper titled "Phase-Separated Nano-Antibiotics Enhanced Survival in Multidrug-Resistant Escherich...
SpyTag-SpyCatcher system: Protein covalent coupling technology
2024-11-07
At the forefront of biomedical research and clinical applications, protein engineering and biomolecular labeling technologies are playing a vital role. However, traditional protein...
Pathogen sensor TLR2
2024-11-05
TLR2, also known as Toll-like receptor 2 (TLR2), also known as CD282, is a pattern recognition receptor (PRR). TLR2 plays a crucial role in recognizing pathogen-associated molecula...
Skin inflammation treatment target IL36R
2024-11-04
IL-36 belongs to the IL-1 superfamily of cytokines and is composed of three agonists (IL-36α, IL-36β, and IL-36γ) and one antagonist (IL-36Ra). IL-36R, also known as IL1RL2, IL-1Rr...
Alzheimer disease therapeutic target TREM2
2024-11-01
Triggering receptor expressed on myeloid cells 2 (TREM2) is a transmembrane receptor of the immunoglobulin superfamily, primarily expressed on microglia in the brain and macrophage...
Introduction to proximity marking technology
2024-10-30
Protein-protein interactions (PPIs) play a crucial role in biological function, participating in cellular biological processes such as cell cycle regulation and signal transduction...