SSTR2 is a therapeutic target for neuroendocrine tumors
SSTR2 is a therapeutic target for neuroendocrine tumors
2024-11-25
The somatostatin receptor (SSTR2) is a member of the G protein-coupled receptor (GPCR) superfamily, expressed in the central nervous system, particularly the hypothalamus, as well ...
Targeting fibroblast activation protein (FAP): advances in CAR-T cell, antibody, and vaccine in cancer immunotherapy
Targeting fibroblast activation protein (FAP): advances in CAR-T cell, antibody, and vaccine in cancer immunotherapy
2024-11-22
Fibroblast activation protein (FAP) is a serine protease with dual enzymatic activity that is overexpressed in various tumor types and in different types of cancer-associated fibro...
Efficient generation of recombinant anti-HER2 scFv with high yield and purity
Efficient generation of recombinant anti-HER2 scFv with high yield and purity
2024-11-19
BackgroundHuman epidermal growth factor receptor 2 (HER2) is a transmembrane glycoprotein consisting of extracellular, transmembrane, and intracellular domains. HER2 overexpression...
Fusion protein linkers: property, design and functionality
Fusion protein linkers: property, design and functionality
2024-11-18
BackgroundIn addition to their widespread application in biological research, such as protein purification and imaging, recombinant fusion proteins have also become a significant c...
Overview of methods used in the study of protein protein interactions
Overview of methods used in the study of protein protein interactions
2024-11-15
Protein-protein interactions are fundamental to cellular structure and function. Most proteins do not function in isolation but rather through interactions with other proteins. The...
Overview of the research methods of protein small molecule interactions
Overview of the research methods of protein small molecule interactions
2024-11-14
Protein-small molecule interactions play a crucial role in drug development, being central to drug mechanisms of action. With the advancement of medicinal chemistry and molecular b...
STEAP1 is a therapeutic target for prostate cancer
STEAP1 is a therapeutic target for prostate cancer
2024-11-12
Six-transmembrane epithelial antigen of the prostate (STEAP1) belongs to the STEAP family, which consists of four members: STEAP1, STEAP2, STEAP3, and STEAP4. First discovered in a...