Immunomodulatory adenosine producer CD73
Immunomodulatory adenosine producer CD73
2024-11-29
CD73 is a 5'-nucleotidase exonuclease (NT5E). The CD73-mediated adenosine pathway converts inflammatory ATP into the immunosuppressant adenosine, which inhibits immune activation t...
Prostate specific membrane antigen PSMA
Prostate specific membrane antigen PSMA
2024-11-26
Prostate-specific membrane antigen (PMSA), also known as glutamate carboxypeptidase II (GCPII) and folate hydrolase (FolH1), is a zinc-dependent metalloproteinase. PSMA is primaril...
SSTR2 is a therapeutic target for neuroendocrine tumors
SSTR2 is a therapeutic target for neuroendocrine tumors
2024-11-25
The somatostatin receptor (SSTR2) is a member of the G protein-coupled receptor (GPCR) superfamily, expressed in the central nervous system, particularly the hypothalamus, as well ...
Targeting fibroblast activation protein (FAP): advances in CAR-T cell, antibody, and vaccine in cancer immunotherapy
Targeting fibroblast activation protein (FAP): advances in CAR-T cell, antibody, and vaccine in cancer immunotherapy
2024-11-22
Fibroblast activation protein (FAP) is a serine protease with dual enzymatic activity that is overexpressed in various tumor types and in different types of cancer-associated fibro...
Efficient generation of recombinant anti-HER2 scFv with high yield and purity
Efficient generation of recombinant anti-HER2 scFv with high yield and purity
2024-11-19
BackgroundHuman epidermal growth factor receptor 2 (HER2) is a transmembrane glycoprotein consisting of extracellular, transmembrane, and intracellular domains. HER2 overexpression...
Fusion protein linkers: property, design and functionality
Fusion protein linkers: property, design and functionality
2024-11-18
BackgroundIn addition to their widespread application in biological research, such as protein purification and imaging, recombinant fusion proteins have also become a significant c...
Overview of methods used in the study of protein protein interactions
Overview of methods used in the study of protein protein interactions
2024-11-15
Protein-protein interactions are fundamental to cellular structure and function. Most proteins do not function in isolation but rather through interactions with other proteins. The...